European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI). ;Workpackage 2: Functional Enviromics

Conditions: psychotic disorders
schizophrenia
10039628

Registration Number: NL-OMON32490

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 625

Inclusion Criteria

Cases:
1. age 16-64
2. Resident within a clearly defined catchment (study) area for a period of at least 6 months
3. First in life contact with physician for suspected psychotic disorder (ICD-10: F20-29; F30-33 [psychosis codings]) during the study period(1th may 2010 to 30st April 2013);Siblings:
1. Age 16 or over
2. Full or half-sibling;Controls:
1. Age 16-64
2. Resident within a clearly defined catchment (study) area for a period of at least 6 months
3. No evidence of current or past treatment with antipsychotic medication

Exclusion Criteria

Cases:
1. Age under 16 or over 64
2. Resident within a clearly defined catchment (study) area for a period of less than 6 months
3. Treatment with anti-psychotic medication for an episode of psychosis outside of the study period
4. Evidence of psychotic symptoms precipitated by an organic cause
5. Transient psychotic symptoms resulting from acute intoxication as defined by ICD-10
6. Illegal migrant (i.e., no legal right to remain in country)
7. Incompetence. If incompetence is caused by psychosis we will approach the patient for informed consent as soon as the treatment for psychosis has made him
competent (according to the responsible physician);Siblings:
1. Age under 16
2. Current or past psychotic disorder (including diagnosis within the time frame of the study)
3. Current or past treatment with antipsychotic medication;Controls:
1. Age under 16 or over 64
2. Resident within a clearly defined catchment (study) area for a period of less than 6 months
3. Current or past psychotic disorder (or treatment within antipsychotic) (including diagnosis or treatment within time frame of the study)
4. Illegal migrant (i.e., no legal right to remain in country)

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Detailed assessment of candidate environmental exposures, at both individual<br /><br>and area levels, by using a case-control design, in a diverse range of settings<br /><br>across Europe</p><br>

Secondary Outcome Measures