The effectiveness and cost effectiveness of screening and stepped-care intervention for alcohol use disorders in the primary care setting

Completed

Conditions: Alcohol Use Disorders
Mental and Behavioural Disorders
Alcohol dependence

Registration Number: ISRCTN55274820

Lead Sponsor: Wales Office of Research and Development (UK)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Male

Target Recruitment: 236

Inclusion Criteria

1. Male
2. Age 18 to 65 (the reason for limiting the age range is that patients above and below this range are catered for by different services in Step 3)
3. Alcohol Use Disorders Identification Test (AUDIT) score more than or equal to eight
4. Diagnosis of an Alcohol Use Disorder according to the Internation Classification of Diseases (ICD-10) (hazardous or harmful drinking, alcohol dependence) as assessed by the baseline research interview
5. Consent to participate in either treatment, and follow-up
6. Willing to nominate an independent informant who the research team can contact to obtain information at baseline and during follow-up, and to nominate a ?locator? who will be able to assist in tracing the subject at follow-up (the independent informant and locator may be the same person)
7. Stable place of residence
8. Living within commuting distance of the practice
9. No treatment for substance misuse in previous 30 days

Exclusion Criteria

1. Current severe mental illness
2. Primary drug dependence (except nicotine and cannabis)
3. Severe physical illness that would preclude participation
4. Current legal problems likely to interfere with follow-up
5. Severe brain damage or mental impairment

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Alcohol consumption obtained using the Time Line Follow-Back interview method (TLFB). This method will be used to provide two measures identical to the primary outcome measures used in project MATCH (Project MATCH Research Group, 1997), namely:<br>1. Mean number of Drinks per Drinking Day (DDD) <br>2. Percentage of Days Abstinent (PDA)

Secondary Outcome Measures

Name	Time	Method
1. Alcohol-related problems: Alcohol Problems Questionnaire (APQ)<br>2. Blood investigations (Gamma-GlutamylTransferase [GGT], Carbohydrate-Deficient Transferrin [CDT-Axis], Mean Corpuscular Volume [MCV])<br>3. Health related Quality of Life (Euroqol questionnaire [EQ-5D], Short Form health surveys [SF-36, SF-12])<br>4. Health economic measures<br>5. Patient compliance (using attendance records)<br>6. Patient and clinician satisfaction using scales developed by the Kings College Group. <br><br>Alcohol consumption and secondary measures 1, 2, & 3 will be included in the baseline assessment to:<br>a. test the adequacy of matching between groups, and <br>b. to act as covariates in subsequent analyses to control for baseline values. <br><br>The Severity of Alcohol Dependence Questionnaire (SADQ), the Situational Confidence Questionnaire (SCQ) and the short Readiness to Change Questionnaire will also be administered at baseline and later investigated as predictors of outcome and care step utilisation.