Analyse of Diagnosis Value of Keloid on 68Ga-RGD PET-CT
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Correlation with clinical symptoms, laboratory tests
研究概览
简要总结
Keloids are often described as benign dermal fibroproliferative lesions characterized by increased growth beyond the boundaries of the original wound margin.Fibroblasts are considered to be the key cellular mediators of fibrogenesis in keloid scars. Thus this prospective study is going to investigate whether 68Ga-RGD PET/CT may provide evidence for diagnosis and evaluate the effectiveness of treatment.
详细描述
Keloids are often described as benign dermal fibroproliferative lesions characterized by increased growth beyond the boundaries of the original wound margin.Fibroblasts are considered to be the key cellular mediators of fibrogenesis in keloid scars. Thus this prospective study is going to investigate whether 68Ga-RGD PET/CT may provide evidence for diagnosis and evaluate the effectiveness of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Patients with a clinical diagnosis of keloids Able to obtain informed consent
排除标准
- •- Pregnant women, children, patients with allergies to contrast media Patients with claustrophobia
研究组 & 干预措施
68Ga-RGD PET/CT
All patients diagnosed with keloid underwent 68Ga-RGD PET/CT.
干预措施: 68Ga-RGD (Drug)
结局指标
主要结局
Correlation with clinical symptoms, laboratory tests
时间窗: 1 year
The clinical assessment of keloids commonly includes the Vancouver Scar Scale for objective scar evaluation, along with laboratory inflammatory markers such as complete blood count (CBC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP).
次要结局
未报告次要终点