Autologous platelet-derived product for palatal wound healing after plastic surgery in comparison with standard surgical gelatin sponges in order to improve post-surgery experience
Not Applicable
- Conditions
- Palatal wound after connective tissue graft harvestOral Health
- Registration Number
- ISRCTN14065920
- Lead Sponsor
- Egas Moniz - Cooperativa de Ensino Superior
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
1. Patients ranging from 18 to 45 years of age
2. Need connective tissue for tunnel operation or coronally flap operation
3. Non-smoking
4. Good oral hygiene
5. No gag reflex
6. No periodontal surgery before at operation site
Exclusion Criteria
1. Systemic disorders (immunologic diseases, uncontrolled diabetes mellitus, ongoing chemotherapy or radiotherapy)
2. Pregnancy/lactation/menstruation
3. Chronic use of anti-inflammatory or analgesic
4. Inability or unwillingness to provide informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain assessed using the Visual Analogue Scale at baseline and for the following 30 days after surgery
- Secondary Outcome Measures
Name Time Method <br> 1. Edema visually measured at 7, 14 and 30 days after surgery<br> 2. Analgesic consumption measured using a personal diary at baseline and for the following 30 days after surgery<br> 3. Healing process measured using early healing index at 7, 14 and 30 days after surgery.<br> 4. Connective tissue graft volume and PRF volumes measured using a periodontal probe during surgery<br>