Effect of Follicle Flushing on Oocyte Fertilization Rate
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Fertilization rate
研究概览
简要总结
The purpose of this study is to investigate the impact of follicular flushing on fertilization rate in women undergoing IVF treatment
详细描述
This will be a prospective observational study on the effect of follicular flushing on fertilization rate in women undergoing IVF treatment.
Oocytes from each woman will be allocated to one of three groups, depending on the aspirate or flush they are recovered from:
Group I= egg retrieved in the follicular fluid of the first aspirate (no flushing) Group II= egg retrieved in the 1st-2nd flush Group III= egg retrieved in the 3rd-5th flush
development and utilization. Pregnancy rates will be reported as a surrogate outcome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Up to 40 years old
- •Both ovaries present
- •Triggering final oocyte maturation using hCG or GnRH agonist
排除标准
- •Egg donation
- •PGD cases
结局指标
主要结局
Fertilization rate
时间窗: Day 1 post oocyte retrieval
Number of fertilized eggs per oocyte retrieved
次要结局
- Maturation rate(Day of oocyte retrieval)
- Blastocyst formation rate(Day 5 post oocyte retrieval)
- Good quality embryos(Day 2 post oocyte retrieval)