Testing of foods and validation of biomarkers to assess nutritional status
Not Applicable
Completed
- Conditions
- specific biomarkers for chicken breast meat, fibers (inulin, beta.glucan), and egg in healthy female and male volunteers
- Registration Number
- DRKS00010133
- Lead Sponsor
- Else Kröner-Fresenius-Zentrum für Ernährungsmedizin der TU MünchenLerhrstuhl für Ernährungsmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
healthy women and men (age 18-40 years)
-BMI <30 kg/m2
-non-smokers
-informed consent
Exclusion Criteria
-smokers
--gastro-intestinal diseases resulting in malabsorption, digestion
-diseases impairing metabolism and excretion
-chronic illness
-acute infection
-intake of antibiotics in the last 6 months
-regular intake of medication (exception: oral contraceptive)
-pregnant and lactating women
-known allergies or intolerance to tested foods
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analysis of metabolites in plasma and urine using LC-MS/MS, GCxGC-MS, and NMR after a single consumption of chickenbreast (100g and 200g), fibers (inulin and beta-glucan), and egg compared to controlfood (for chickenbreast and egg:rice; for fibers:toastbred). Timepoints for taking blood samples are 0, 1,2,4,6,12,and 24 hours. Timepoints for urinesampling are 0-1h, 1-2h, 2-4h, 4-6h, 6-12h, 12-24h, 48h.
- Secondary Outcome Measures
Name Time Method