Non-invasive Evaluation of Volume Status Using Exhaled Carbon Dioxide and Pulse Contour Analysis

Not Applicable

Completed

• Conditions: Changes in Cardiac Output

• Registration Number: NCT02070861
• Lead Sponsor: Oslo University Hospital

Brief Summary

The investigators hypothesize that changes in blood circulation can be reflected by exhaled CO2 provided CO2-production in the tissues and ventilation from the lungs are stable. The investigators want to explore changes in cardiac output (the amount of blood being pumped out of the heart each minute) in patients using different devices: an esophagus ultrasound device measuring cardiac output, a finger cuff measuring blood pressure and cardiac output, and exhaled carbondioxide in the patients' breath measured by the ventilator.

The investigators investigate patients after bypass surgery or heart valve replacement, and induce changes in cardiac output with passive leg raise or ventricular pacing.

Detailed Description

Measurements with the finger cuff (pulse contour analyses) were aborted due to technical difficulties.

Study Timeline

• Study First Submitted: 2014-02-23
• Study First Submitted QC: 2014-02-24
• Study First Posted: 2014-02-25
• Study Start: 2014-04
• Primary Completion: 2015-06
• Study Completion: 2015-06
• Status Verified: 2018-04
• Last Update Submitted: 2018-04-14
• Last Update Posted: 2018-04-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• Persons 18 years or older scheduled to undergo arteriocoranary bypass surgery or aortic valve replacement.

Exclusion Criteria

• Esophageal pathology, EF <40%

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Changes in cardiac output	5 Minutes

Trial Locations

Locations (1)

Oslo University Hospital, Ullevål; 🇳🇴 Oslo, Norway