Non-invasive Volume Evaluation With Exhaled Carbon Dioxide and Pulse Contour Analysis (Nexfin)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- Changes in cardiac output
研究概览
简要总结
The investigators hypothesize that changes in blood circulation can be reflected by exhaled CO2 provided CO2-production in the tissues and ventilation from the lungs are stable. The investigators want to explore changes in cardiac output (the amount of blood being pumped out of the heart each minute) in patients using different devices: an esophagus ultrasound device measuring cardiac output, a finger cuff measuring blood pressure and cardiac output, and exhaled carbondioxide in the patients' breath measured by the ventilator.
The investigators investigate patients after bypass surgery or heart valve replacement, and induce changes in cardiac output with passive leg raise or ventricular pacing.
详细描述
Measurements with the finger cuff (pulse contour analyses) were aborted due to technical difficulties.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persons 18 years or older scheduled to undergo arteriocoranary bypass surgery or aortic valve replacement.
排除标准
- •Esophageal pathology, EF <40%
研究组 & 干预措施
Comparing cardiac output changes
Explore the relationship between changes in cardiac output measured with eosophagal Doppler, the volume-clamp-method and exhaled CO2 during ventricular pacing and passive leg raise.
Measurements with the volume-clamp-method were aborted due to technological difficulties.
干预措施: Ventricular pacing and passive leg raise (Other)
结局指标
主要结局
Changes in cardiac output
时间窗: 5 Minutes
次要结局
未报告次要终点
研究者
Ingrid Elise Hoff
MD
Oslo University Hospital