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临床试验/NL-OMON32339
NL-OMON32339已完成不适用

Immune regulation in Common Variable Immunodeficiency: the role of apoptosis and regulatory T cells. - Immune regulation in CVID

niversitair Medisch Centrum Utrecht0 个研究点目标入组 65 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
65

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
2 至 99(—)

入选标准

  • Diagnosis of CVID; based on recurrent respiratory tract infections, decreased total serum IgG (<-2SD) and impaired specific antibody production after vaccination. Both patients with and without auto immune phenomena will be included.
  • Diagnosis of XLA; based on the (almost complete) absence of B cells and a mutation in the Btk gene.

排除标准

  • Both patients groups: uncertainty about the diagnosis. Acute and/or severe infections at the moment of inclusion.
  • XLA patients: existence of auto immune symptoms

研究者

发起方
niversitair Medisch Centrum Utrecht

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