Nasal Anatomical and Pathological Variants in Patients With Antrochoanal Polyps
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- presence of anatomical and pathological variants in CT scan and endoscopic examination
研究概览
简要总结
The goal of this observational study is to learn about anatomical and pathological variants in patients with antrochoanal polyps trying to find a key to its pathogenesis Participants will have nasal endoscopic examination and CT nose and paranasal sinuses.
we will compare patients with antrochoanal polyps and other patients with unilateral sinonasal disease regarding anatomical and pathological variants.
详细描述
This study was conducted at Otolaryngology department, Minia University Hospital, Minia, Egypt. The study was approved by the Institutional Review Board at Minia University.
The study participants were recruited from patients complaining from unilateral sinonasal disease attending outpatient clinic.
we selected 40 patients with ACPs who had the following inclusion criteria: 1-radiologically diagnosed based on CT nose and PNS. 2-histopathologically diagnosed as ACP. The radiological diagnosis is based on seeing low attenuated soft tissue mass filling the maxillary antrum and extending through the middle meatus into the nasal cavity and directs towards the post nasal opening. We excluded: 1- patients with history of maxillofacial trauma. 2- patients who had previous nasal surgery.
To be more objective, a control group of 40 patients who had unilateral sinonasal disease other than ACP was formed.
We assessed multislice computed tomography (CT) nose and paranasal sinus images by Toshiba aquilion CT scanner. Axial and coronal 250mm cuts were obtained.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •radiologically diagnosed based on CT nose and PNS.
- •histopathologically diagnosed as ACP.
排除标准
- •patients with history of maxillofacial trauma.
- •patients who had previous nasal surgery.
结局指标
主要结局
presence of anatomical and pathological variants in CT scan and endoscopic examination
时间窗: 6 months
Both study and control groups were compared regarding anatomical and pathological variations in the nose. These variants include: deviated nasal septum, concha bullosa, paradoxical middle turbinate and uncinate process insertion (to lamina papyrecea or roof of ethmoid or middle turbinate). We also compare between them according to presence of retention cyst in CT in contralateral side In the cases with deviated nasal septum, the septal deviation was seen if it is towards the side of the lesion or towards the opposite side according to its convexity. We also evaluate the sclerosis on thickening of the bony wall of the para nasal sinus as an indication of chronic inflammation.
次要结局
未报告次要终点
研究者
Maisara Mohamed
assistant lecturer of otorhinolaryngology
Minia University