Brain Function and Decision-Making
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Change in Accuracy of Empathic Pain Judgments
研究概览
简要总结
This study is about how brain function and structure is different between two universities. Participant in this project will contribute to a better understanding of how universities affect the brain.
详细描述
Some study details are purposely omitted at this time to preserve scientific integrity. Now that the study is completed, full details are included below.
The true purpose of this study was to investigate the psychometric properties of the two computer tasks that participants completed. Specifically, researchers wanted to know if they would be able to accurately measure motivated empathy. To better understand this, participants were asked to rate images of people expressing pain and were told that these were either students from their university or students from a different university. This was not the case. The faces shown were random images produced for a research study.
Researchers also wanted to know if they could accurately measure moral decision making and how those judgments relate to aggression. To examine this, participants were asked whether various scenarios were immoral and then asked about aggressive tendencies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Undergraduate students aged 18 - 35 years of age
- •No current or regular use of prescribed or illicit psychoactive drugs
- •Free of major health problems (e.g., diabetes, HIV, Parkinson's disease)
- •Free of a neurological or psychiatric disorders
- •No current drug abuse (e.g., recreational drug use, average alcohol intake in excess of 4 drinks per day).
- •Right hand dominant
- •Free of claustrophobia
- •Free of pregnancy or suspected pregnancy
- •Absent MRI risk factors (e.g., implanted medical device, body mass index > 35, braces)
- •Free of medical conditions that render individuals with overly sensitive hearing
- •No colorblindness
排除标准
- •Not meeting the inclusion criteria listed above.
结局指标
主要结局
Change in Accuracy of Empathic Pain Judgments
时间窗: Baseline to 3 hours
Difference in pain judgment scores rated from 1 (low) to 4 (high) between antisocial vs prosocial empathy trials
Change in Prefrontal Cortex Brain Activity Assessed by fMRI
时间窗: Baseline to 3 hours
Blood-Oxygen-Level-Dependent signal change in the cognitive empathy brain network will be assessed using functional MRI
次要结局
未报告次要终点