CTRI/2022/04/042101已完成不适用
Randomized controlled study comparing the efficacy of oral Clonidine and intravenous Dexmedetomidine in maintaining the hemodynamic stability in patients undergoing major spine surgery
未提供1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2022年2月5日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Measurement of Systolic, diastolic and mean blood pressures during surgery. Heart rate, number of episodes of hypotension and hypertension will also be recorded
研究概览
简要总结
This is a double blind randomized clinical trial being conducted by a postgraduate on patients undergoing major spine surgery. The hemodynamic stablity of these patients is being assessed after receiving either oral Clonidine or Intravenous Dexmedetomidine during surgery.Also the blood loss in these patients is being compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA physical status 1 and 2
- •2 or more level spine instrumentation.
排除标准
- •ASA physical status 3 and 4
- •Patients on Chronic Beta blocker therapy
- •Patients with uncontrolled blood pressure
- •Patients with renal or liver disease
- •Patients on ACE inhibitors/ ARBs.
结局指标
主要结局
Measurement of Systolic, diastolic and mean blood pressures during surgery. Heart rate, number of episodes of hypotension and hypertension will also be recorded
时间窗: Recordings will be baseline before intubation, after intubation, after proning the patient and every 15 minutes till end of surgery.
次要结局
- 1. To compare intraoperative analgesic requirements, blood loss and recovery time from anesthesia(Total dose of fentanyl and propofol needed during surgery and blood loss at the end of surgery will be calculated. All measurements will be completed by the end of surgery)
研究者
研究点 (1)
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