Residual or Recurrent Obstruction After Septal Myectomy

Completed

• Conditions: Hypertrophic Obstructive Cardiomyopathy

• Registration Number: NCT05687487
• Lead Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital

Brief Summary

The goal of this observational study is to report the outcomes after septal myectomy in young children and infants and identify the mechanisms of residual or recurrent obstruction after surgery. in The main question\[s\] it aims to answer are:

* What is the early and mid-term results of septal myectomy in young children and infants with severe and extensive obstructive hypertrophic cardiomyopathy (HCM)?

* What are the mechanisms of residual or recurrent obstruction?

Echocardiography and clinical course of children and infants under the age of 14 who underwent septal myectomy for hypertrophic obstructive cardiomyopathy from January 2013 to December 2020 will be followed up.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-02-01
• Status Verified: 2023-01
• Study First Submitted: 2023-01-06
• Study First Submitted QC: 2023-01-13
• Last Update Submitted: 2023-01-13
• Study First Posted: 2023-01-18
• Last Update Posted: 2023-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Clinical diagnosis of hypertrophic obstructive cardiomyopathy (HOCM)
• Age young than 14 years
• Patients who have undergone septal myectomy

Exclusion Criteria

• older than 14 years old;
• secondary left ventricular hypertrophy (LVH) related to subaortic stenosis or aortic stenosis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
death	through study completion, an average of 1 year	postoperative death during follow-up

Secondary Outcome Measures

Name	Time	Method
recurrent obstruction	through study completion, an average of 1 year	postoperative recurrent obstruction during follow-up