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临床试验/NCT07186608
NCT07186608已完成不适用

Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome (SBS) Through Microbial and Metabolic Mechanisms That Drive Functional Compensation.

Jinling Hospital, China1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2025年2月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
1
主要终点
Determination of nitrogen content

研究概览

简要总结

Ten patients with short intestines in clinical practice were intervened with dietary fiber. Serum and feces before and after the dietary fiber intervention were collected, and relevant indicators of nutrition and intestinal barrier were collected to observe the improvement of dietary fiber on patients with short intestines

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All participants in Cohort 1 were recruited at the Eastern Theatre Command General Hospital (Nanjing, China) and provided written informed consent. The primary inclusion criterion was a confirmed diagnosis of type II or type III short bowel syndrome in patients aged 18
  • 70 years. Participants were excluded if they had other gastrointestinal diseases, malignant tumours, autoimmune diseases, infectious diseases or renal insufficiency (severe kidney disease with creatinine levels exceeding 3.0 mg/dL), or if they had taken antibiotics for more than three days within the preceding three months.

排除标准

  • 未提供

结局指标

主要结局

Determination of nitrogen content

时间窗: From enrollment to the end of treatment at 2 weeks

次要结局

未报告次要终点

研究者

发起方
Jinling Hospital, China
申办方类型
Other
责任方
Principal Investigator
主要研究者

Wang Xinying

Chief Physician

Jinling Hospital, China

研究点 (1)

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