Analysis of the Early Development of the Visual Function in Extreme Premature Infants Under 28th Weeks of Gestation
- Conditions
- Vision
- Registration Number
- NCT00768586
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
The aim of this study is to collect data on the early visual development of extreme premature infants. The method is the measurement of flash visual evoked potentials and the study population includes premature infants under the 28th weeks of gestation, who have normal cranial ultrasound examinations, normal aEEG, no clinical neurological symptoms and who have a normal ophthalmological status.
fVEP measurements were recorded from the first week of life every second week until term.
The fVEP recordings were performed in active sleep, in stable premature infants, who were continuously monitored. The Nihon Kohden Neuropack 8 was used, the stimulus frequency was 0,5 Hz, artefact free averages were analyzed.
The measurements were analyzed according to the presence and absence of known waveforms, their latencies and amplitudes. Longitudinal analysis was performed to analyse the effect of extrauterine visual development on fVEP with growing gestational ages.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
- All premature infants under the 29th week of gestation entering our ward.
- Infants with intracranial abnormalities, cerebral malformations, neurological symptoms or known eye pathology.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Latency and Amplitude of Visual Evoked Potential waveforms measured in the first week of life than every second week prospectively until term. Until term
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Medical University Vienna, Department of Pediatrics, Neonatology
🇦🇹Vienna, Austria