EFFECT OF INTRAVENOUS PARACETAMOL AS PREEMPTIVE ANALGESIC FOR POST OPERATIVE ANALGESIA IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of preemptive use of intravenous paracetamol for post operative pain through visual analogue score (VAS) on patients undergoing elective laparoscopic cholecystectomy
研究概览
简要总结
This is a prospective, double-blind,randomised control study to be conducted in the general surgery operation theater under the Department of Anesthesiology And Critical Care, GMCH. The study will be carried out in adult patients of both sexes, posted for elective laparoscopic cholecystectomy . the aim of the study is compare the efficacy of preemptive use of intravenous 10mg/kg paracetemol and placebo for post operative analgesia. The primary obesctive is to evaluate the efficacy of preemptive use of intravenous paracetemol for post operative pain through VAS on the patients undergoing elective laparoscopic cholecystectomy and the secondary objectives is to evaluate post operative total rescue analgesic consumotion in first 24 hr and to monitor and compare the intraoperative and postoperative vitals among the two groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I, II Adults of age 18years-60 years Duration of surgery less than equal to 90min.
排除标准
- •Patient refusal History of allergy to the paracetemol Bleeding disorder History of use of paracetemol, nsaids,opids within 48hrs for chronic pain Surgeries converted to open cholecystectomies.
结局指标
主要结局
To evaluate the efficacy of preemptive use of intravenous paracetamol for post operative pain through visual analogue score (VAS) on patients undergoing elective laparoscopic cholecystectomy
时间窗: To evaluate the efficacy of preemptive use of intravenous paracetamol for post operative pain through visual analogue score (VAS) on patients undergoing elective laparoscopic cholecystectomy, | T1-15min, T2- 30 min, T3- 1 hr, T4-2hr, T5- 8hr, T6- 12 hr, T7- 24hr post operatively
次要结局
- To evaluate total consumption of rescue analgesic in first 24 hr.(To compare the intraoperative and postoperative vitals among the two groups.)
研究者
Dr Daisy Rani Das
Gauhati Medical College and Hospital