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Evaluation of serum haptoglobins levels and cell free hemoglobin as predictors of mortality in patients with perforation peritonitis

Not Applicable
Conditions
Health Condition 1: K650- Generalized (acute) peritonitis
Registration Number
CTRI/2021/06/034313
Lead Sponsor
Government medical college and hospital chandigarh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patient willing for participation in the study.

All patients presenting in emergency with perforation peritonitis on clinical examination and radiological investigations.

Exclusion Criteria

1.Patients operated outside GMCH and later referred to the center.

2.Patients with other causes of hyperhaptoglobinemia (raised cell free hemoglobin with increased haptoglobin), i.e, previously diagnosed cases of hepatitis, amyloidosis, collagen diseases, lymphoma, leukemia, steroid use, aplastic anaemia, or nephrotic syndrome.

3. Patients with known history of congenital causes of haemolytic anaemia (AIHA, hereditary spherocytosis, sickle cell disease, thalassemia), and cirrhosis, which will lead to persistent decrease in serum haptoglobin levels.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
serum haptoglobin and cell free hemoglobin levelsTimepoint: 1 month
Secondary Outcome Measures
NameTimeMethod
combination of serum haptoglobins and cell free hemoglobins as predictors of mortality in patients with perforation peritonitisTimepoint: 1 month
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