ISRCTN68382401已完成未知

Barrett’s oESophagus Trial 3 (BEST3): randomised controlled trial comparing the Cytosponge™-TFF3 test with usual care to facilitate the diagnosis of oesophageal pre-cancer in primary care.

Cambridge University Hospitals NHS Foundation Trust and University of Cambridge0 个研究点目标入组 13,514 人开始时间: 2017年1月19日最近更新: 2024年2月27日

适应症

试验速览

2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30075763 protocol 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32738955/ results (added 04/08/2020) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36627580/ secondary results: patient experience (added 11/01/2023) 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/35393308/ Patient-reported experiences and views (added 14/02/2024)

•1. Aged 50 years and over
•2. Records of at least 6 months of prescription for acid-suppressant medication in the last year

•Current exclusion criteria as of 15/08/2017:
•1. Recorded regular prescriptions of NSAIDs
•2. Recorded upper GI endoscopy in the previous 5 years as identified from the practice database
•3. Recorded diagnosis of a current or previous oro-pharynx, oesophageal or gastro-oesophageal tumour
•4. Recorded diagnosis of Barrett’s oEsophagus (BE)
•5. Unable to attend the GP surgery
•6. Deemed not fit enough by their GP
•Previous exclusion criteria:
•1. Recorded regular prescriptions of NSAIDs
•2. Recorded regular prescription of Clopidogrel
•3. Recorded upper GI endoscopy in the previous 5 years as identified from the practice database
•4. Recorded diagnosis of a current or previous oro-pharynx, oesophageal or gastro-oesophageal tumour
•5. Recorded diagnosis of Barrett’s oEsophagus (BE)
•6. Unable to attend the GP surgery
•7. Deemed not fit enough by their GP

发起方

Cambridge University Hospitals NHS Foundation Trust and University of Cambridge