Surgical Approach to Accelerate the Orthodontic tooth movement

Phase 1

Completed

Conditions: Subjects undergoing Orthodontic treatment for esthetic reasons, but all subjects will be healthy as per our inclusion criteria

Brief Summary: This split-mouth design will compare the rate of orthodontic tooth movement with micro - osteoperforation. The study contains 30 subjects in experimental group . Three micro-osteoperforations will be performed with lance pilot drill, in the extraction site distal to canine just before retraction . The level of alveolar bone density will be measured at T1 (1 week) and T2 (1 month) time interval . The GCF biomarkers for orthodontic tooth movement will be measured at 0,7,14,21 and 28 days. The treatment duration will be of 4 months / till the completion of canine retraction.

Recruitment & Eligibility

Inclusion Criteria

Patient with Angleâ€™s Class I malocclusion, Angleâ€™s Class I bimaxillary malocclusion and Class II bimaxillary and Angleâ€™s class II div I malocclusion requiring 1st premolar extraction and bilateral maxillary canine ditalization were included 2.
Only those patients were included in which atraumatic 1st premolar extraction was done.
The performance of MOPs and canine retraction was done at least 4 months after the extraction procedure to remove the bias due to the RAP induced due to extraction.
Canine roots to be in cancellous bone.
Patient with good oral hygiene.

Exclusion Criteria

Patients on long term use of antibiotics, phenytoin, cyclosporine, anti-inflammatory drugs were discarded 2.
Patients on systemic corticosteroids and calcium channel blockers were not included in the study.
Patients with history of periodontal therapy 4.
Patients with untreated caries, gingivitis and h/o smoking were not included in the study.

Primary Outcome Measures

Name	Time	Method
to observe the rate of orthodontic tooth movement with micro-osteoperforations	Total time period - 4 months \| Patient will be recalled at every 7,14, 21, 28 days for first month and thereafter at every 28 days

Secondary Outcome Measures

Name	Time	Method
To check the level of biomarkers at different time points and to assess the change in bone density level	0, 7,14, 21, 28 days

Locations (1): Subharti Dental college, SVSU, Meerut, UP
🇮🇳
Meerut, UTTAR PRADESH, India
Subharti Dental college, SVSU, Meerut, UP
🇮🇳Meerut, UTTAR PRADESH, India
Dr Preeti
Principal investigator
9336594653
drpradeepraghav@gmail.com