Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Al-Azhar University
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Evaluation of strepetoccous mutant and lactobacilli from sample of saliva
Study Overview
Brief Summary
Fiber reinforced composite resin space maintainer
Detailed Description
Evaluation of the antimicrobial fiber reinforced composite resin space maintainer modified by silver nano particles.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 4 Years to 9 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Premature loss of primary molar.
- •Presence of teeth on the mesial and distal sides of the extraction space.
- •Normal primary molar relation.
- •No root resorption of abutment teeth.
- •Presence of a succedaneous tooth bud.
- •Absence of pathology on the eruption track of the succedaneous tooth.
- •The age will be ranged from 4 to 9 years.
Exclusion Criteria
- •Carious buccal and lingual surface of abutment teeth.
- •Absence of teeth on the mesial and distal sides of the extraction.
Arms & Interventions
Fiber reinforced composite space maintainer
12 children received fiber reinforced composite (FRC) space maintainer without silver nanoparticle.
Intervention: Fiber reinforced composite resin space maintainer (Device)
Fiber reinforced space maintainer with silver nano particles
12 children received fiber reinforced composite (FRC) space maintainers modified with silver nanoparticles.
Intervention: Fiber reinforced composite resin space maintainer (Device)
Outcomes
Primary Outcomes
Evaluation of strepetoccous mutant and lactobacilli from sample of saliva
Time Frame: 6 month
Streptococcus mutants : One loop (1/1000th ml of sample) was inoculated on the Mitis Salivarius (MSA)\* agar with 0.2 U/ml bacitracin and sucrose (15% w/v) bacitracin. The plates were incubated aerobically ( 5% CO2) at 37°C for 48 h.(10) For determination of S. mutans count: After 48 h , colony characteristics were studied and the number of colony forming units of SM (CFU/ml) in saliva was determined manually . Lactobacilli : One loop (1/1000th ml of sample) was inoculated on the Rogosa \*\*SL agar plate. The plates were incubated aerobically ( 5% CO2) at 37°C for 48 h.(11) For determination of lactobacilli count: After 48 h , colony characteristics were studied and the number of colony forming units of lactobacilli (CFU/ml) in saliva was determined manually
Secondary Outcomes
No secondary outcomes reported
Investigators
Mohamed Nada Mohamed Elsadany
Mohamed nada Mohamed elsadany
Al-Azhar University