Acupuncture Feasibility Trial for Dyspnea in Lung Cancer

Phase 1

Completed

• Conditions: Dyspnea; Lung Cancer
• Interventions: Procedure: Acupuncture

• Registration Number: NCT02094950
• Lead Sponsor: Abramson Cancer Center at Penn Medicine

Brief Summary

This is a single arm clinical trial to establish the feasibility of conducting a clinical trial of acupuncture in reducing dyspnea among lung cancer survivors who have completed chemoradiotherapy. Twelve subjects with dyspnea will be recruited to this clinical trial. Up to 10 sessions of acupuncture will be delivered over the course of 8-10 weeks. The primary outcome will be dyspnea as measured by the English version of the Cancer Dyspnea Scale at the completion of the intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2014-03-20
• Study First Submitted QC: 2014-03-20
• Study First Posted: 2014-03-24
• Primary Completion: 2015-07-15
• Study Completion: 2015-07-15
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-22
• Last Update Posted: 2019-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Diagnosis of Lung Cancer (Non small cell and small cell both eligible)
• Completion of concurrent CRT at least 6 months prior to randomization.
• Dyspnea which worsened after Chemoradiotherapy, leading to a ATS dyspnea score greater than or equal to 2 (Walks slower than people of the same age on the level because of breathlessness or has to stop for breath when walking at own pace on level)
• Ability to understand written English -Willingness to adhere to all study-related procedures
• Age 18 years old
• ECOG Performance Status 1-3

Exclusion Criteria

• Current receipt of therapy for treatment related pneumonitis for 3 weeks.
• Surgical resection of this LC (lobectomy or pneumonectomy)
• Another organic cause of dyspnea necessitating treatment (eg pleural effusion appropriate for thoracentesis, rapidly progressive intrathoracic recurrence, symptomatic pulmonary embolus after CRT, untreated anemia with hemoglobin8 g/dL)
• Current bleeding disorder by history
• Life expectancy of 12 weeks, as assessed by primary oncologist

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Lung Cancer Patient with Dyspnea	Acupuncture	-

Primary Outcome Measures

Name	Time	Method
Dyspnea	10 weeks

Trial Locations

Locations (1)

Abramson Cancer Center of the University of Pennsylvania; 🇺🇸 Philadelphia, Pennsylvania, United States