Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias
- Conditions
- Cardiac Arrythmias
- Interventions
- Other: 3D ImagingOther: Late Gadolinium Enhancement (LGE)
- Registration Number
- NCT02741180
- Lead Sponsor
- NYU Langone Health
- Brief Summary
The primary purpose of this study is to improve the quality of Magnetic Resonance Imaging in patients with heart arrhythmia. Investigators will recruit 105 patients with arrhythmia and 30 control volunteers over 3 years and will use two arrhythmia-tolerant imaging methods for diagnosis.
- Detailed Description
In the proposed research, investigators will extend conventional cardiac magnetic resonance methods to enable the creation of high-quality cine CMR images in the presence of multiple kinds of arrhythmia. Two arrhythmia-tolerant imaging methods will be adopted, which are particularly useful in arrhythmia: 1) 3D imaging, which is useful for many purposes, including "road mapping" of electrophysiology (EP) procedures, and 2) late gadolinium enhancement (LGE), which is useful for delineating abnormal myocardium, including fibrotic regions that can serve as sources of arrhythmias.
Recruitment & Eligibility
- Status
- SUSPENDED
- Sex
- All
- Target Recruitment
- 135
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Healthy Control Late Gadolinium Enhancement (LGE) - Patients with Arrhythmias 3D Imaging - Patients with Arrhythmias Late Gadolinium Enhancement (LGE) - Healthy Control 3D Imaging -
- Primary Outcome Measures
Name Time Method Paired-sample Wilcoxon signed rank test to evaluate measures on Likert scales 3 Years Paired-sample t tests for quantitative measures of intensity of image artifacts 3 Years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
New York University School of Medicine
🇺🇸New York, New York, United States