Comparison of the effectiveness of morphine and ketorolac in the treatment of acute migraine attacks

Phase 3

Recruiting

• Conditions: acute migraine attack.; Migraine

• Registration Number: IRCT20210129050168N1
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 27 June 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

being at least 18 years old
having a migraine history for at least 1 year
having 2 -10 migraine attacks per month
if the patient is receiving a prophylactic medication, they shouldn't have changed or interrupted it at least for the previous 3 months

Exclusion Criteria

The patient is allergic to the studied drugs
Contraindications to the use of these drugs such as basilar migraine(migraine with brainstem aura) and hemiplegic migraine, cerebrovascular and cardiovascular diseases, uncontrolled hypertension, ergotamine-containing drugs and monoamine oxidase inhibitors
Blood dyscrasias
Chronic painful diseases other than migraine
Chronic hepatic, renal, and pulmonary failure
Drug addiction
Pregnancy
Type 1 and 2 diabetes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of medication on reducing pain intensity based on visual analog scale (VAS) questionnaire. Timepoint: 0 minutes- 60 minutes -120 minutes. Method of measurement: Ten-point VAS questionnaire based on pain intensity.

Secondary Outcome Measures

Name	Time	Method
Effects of headache on a person's quality of life and daily activities, and a score above 50 is nominated as a candidate for migraine. Timepoint: 0 minutes- 60 minutes -120 minutes. Method of measurement: A standard questionnaire to assess demographic characteristics and headache, including disability (test [HIT] -6).