NL-OMON29744已完成不适用
Is the presence and development of microvascular disease in type 1 diabetes related to changes in brain structure and cognitive function? - Microvascular disease and brain structure and function
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •age 18-45 years
- •right-handedness:
- •Dutch as a native language
排除标准
- •alcohol abuse which is defined as more than 20 gram of alcohol per day,
- •(history of) use of MDMA, cocaine, heroin, methylphenidate, current regular use of cannabis, or history of regular use on a daily basis for at least 5 years,
- •current use of benzodiazepines, non-selective beta blockers, oral steroids (>7.5 mg/day),
- •psychiatric disorder warranting psychotropic treatment (e.g. tranquillisers, anti-depressants)
- •anaemia or thyroid dysfunction,
- •history of severe head trauma accompanied by loss of consciousness,
- •Parkinson*s disease
- •inability to undergo MRI (claustrophobia, metal implants, BMI>35),
- •visual acuity < 0.3 at the last ophthalmologic examination
- •diabetes duration < 10 years
- •all other factors that can possibly contribute to cognitive decline or altered cerebral blood flow
研究者
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