ACTRN12612000811808已完成未知
The effects of small intestinal L-tryptophan infusions on antropyloroduodenal motility, gut hormone release, blood glucose control and energy intake in normal weight subjects.
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 50 Years（—）
- 性别
- All
入选标准
- •Male and female (BMI 18-25 kg/m2) subjects, aged between 18 - 50 years, will be included in the study. All subjects will be required to be weight-stable (i.e. < 5 % fluctuation in their body weight) at study entry, as determined by their self-reported weight in the preceding 3 months, and will be required to maintain their normal physical activity over the course of the study.
排除标准
- •Significant gastrointestinal symptoms, disease or surgery, use of prescribed or non-prescribed medications (including vitamins and herbal supplements) which may affect energy metabolism, gastrointestinal function, body weight or appetite (eg domperidone, orlistat, green tea extracts, Astragalus, St Johns Wort etc.), as well as SSRIs (selective serotonin reuptake inhibitors), lactose intolerance/other food allergy, diabetes mellitus, as defined by fasting glucose >6.9 mmol/l and/or glycated haemoglobin =6.2 %, epilepsy, cardiovascular or respiratory diseases, current intake of > 2 standard drinks on > 5 days per week, current smokers of cigarettes/cigars/marijuana, restrained eaters (score > 12 on the three factor eating questionnaire), vegetarians, in female subjects, pregnancy or lactation.
研究者
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