How does exercise impact bone turnover in people with and without Type 1 diabetes?

Not Applicable

Completed

• Conditions: Type 1 diabetes; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN10346879
• Lead Sponsor: ewcastle University

Brief Summary

2020 Results article in http://dx.doi.org/10.1136/bmjdrc-2020-001779 (added 03/09/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-26
• Study Completion: 2019-10-01
• Last Update Posted: 13 September 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Aged 18-65 years old
2. Clinically diagnosed Type 1 diabetes
3. Treated with exogenous insulin (pump or injection)
4. Free from diabetes complications

Exclusion Criteria

1. Type 1 diabetes participants duration of disease less than 1 year
2. Type 1 diabetes HbA1c >10%
3. Musculoskeletal injury

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in CTX, procollagen type 1 N-Terminal propeptide, and parathyroid hormone from rest, to immediately after exercise. These will be measured by routine biochemical assay.

Secondary Outcome Measures

Name	Time	Method
Changes in ionised calcium, phospohate, calcium, albumin from rest, to immediately after exercise. These will be measured by routine biochemical assay.