Does exogenous glucose-dependent insulinotropic polypeptide (GIP) effect gastric emptying and glycaemic response to small intestinal nutrient in critically ill patients?
Phase 2
Recruiting
- Conditions
- Blood Glucose ControlCritical illnessMetabolic and Endocrine - Other metabolic disorders
- Registration Number
- ACTRN12612000488808
- Lead Sponsor
- Adam Deane
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Mechanically ventilated critically ill patients.
Suitable for, or receiving post-pyloric nutrition.
Likely to stay ventilated for at least 48 hours.
Exclusion Criteria
History of diabetes
Pregnancy
Haemoglobin <80g/L
Contraindication to enteral feeding
Previous surgery to small intestine
Any gastrointestinal surgery during admission
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine if exogenous glucose-dependent insulinotropic polypeptide (GIP) will lower fasting and nutrient stimulated glycaemia[Blood glucose will be measured at 30min intervals between t=0-360min]
- Secondary Outcome Measures
Name Time Method