A randomized controlled trial to asses the effect of vitamin D in patients with atopic dermatitis.
Phase 3
Completed
- Conditions
- atopic eczema10014982
- Registration Number
- NL-OMON37457
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Age 18 years or older. Mild to moderate atopic dermatitis, with a SCORAD score between 15 and 40. Informed consent.
Exclusion Criteria
- Oral use of prescribed vitamin D or calcium supplements.
-Pregnancy
-Lactating women
-Patients who receive specialized treatment for disorders in calcium homeostasis and/or liver and kidney diseases.
-Inflammatory skin diseases unrelated to atopic dermatitis, except acneiform eruption.
-Sunny holiday during the previous 6 weeks
-Use of sunbeds or UV-therapy.
-Allergy/intolerance for ingredients used in the study medications.
-Previously documented non-compliance.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main endpoint will be the number of, and time to, exacerbation of atopic<br /><br>dermatitis. To assess a profile of which patients are better to treatable with<br /><br>topical vitamin D, filaggrin mutation and vitamin D levels at the start of<br /><br>treatment will be assessed. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The quality of life in patients using the different treatment and the<br /><br>difference of transepidermal water loss between the two treatment groups. </p><br>