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临床试验/NCT07465523
NCT07465523招募中不适用

A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

Ahmet Yesildag1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2026年3月4日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
90
试验地点
1
主要终点
A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

研究概览

简要总结

In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant masses will be evaluated.

详细描述

The aim of this study is to reveal the role of differences in the resistive index of masses and surrounding tissue in distinguishing between benign and malignant masses using a new approach in the evaluation of breast masses with Doppler ultrasound. The minimum, maximum, and average RI values obtained from the mass and healthy breast tissue will be recorded. The relative RI value difference will be calculated from the RI values of the mass and healthy tissue. Based on the pathology results, the cases will be divided into two groups: benign and malignant. The threshold values of these values in malignant and benign masses will be determined and compared. Additionally, vascular index values in breast masses will be calculated and compared using the relatively new Doppler Microvascular Flow method.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Those with solid breast masses
  • Female patients
  • Those with pathology results

排除标准

  • Hypovascular masses
  • Cystic breast masses
  • Cases with mastitis

结局指标

主要结局

A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

时间窗: 3-4 months

ROC curve analysis will be applied for the diagnostic performance of relative RI change in benign and malignant lesions.

次要结局

未报告次要终点

研究者

发起方
Ahmet Yesildag
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Ahmet Yesildag

Prof. Dr.

Karamanoğlu Mehmetbey University

研究点 (1)

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