Study of Risk Factors for Intraductal Papillary Mucinous Neoplasms Degeneration at the Nancy CHRU (IPMN)
- Conditions
- Study of Risk Factors for IPMNs Degeneration at the Nancy CHRU
- Registration Number
- NCT04901364
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Cystic lesions of the pancreas are frequent with a risk of degeneration into adenocarcinoma with pejorative prognosis.
IPMNs require characterization to clarify their potential for degeneration. Clinical and morphological risk factors for degeneration determine the monitoring rate and the indication for pancreatic surgery.
Pancreatic surgery remains invasive with high morbidity and mortality rates.
- Detailed Description
This is a monoservice and monocentric retrospective study at the Nancy CHRU. We will study the risk factors for IPMNs degeneration in order to determine the most sensitive and specific.
To do this, we will use high-grade dysplasia or invasive cancer on the histological analysis of surgical specimens as the primary endpoint.
The study population will be patients with Branch Duct, Main Duct or mixed IPMNs operated at the Nancy CHRU between September 2009 and October 2021.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 57
- Patients with a Branch Duct, Main Duct or mixed IPMNs operated at the Nancy CHRU between September 2009 and October 2021, adults and without legal protection measures
- IPMNs not operated
- Pancreatic cancer without IPMNs
- Patients whose state of health contraindicates pancreatic surgery
- Non-adult patient
- Patients under legal protection
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method High-grade dysplasia or invasive cancer 12 years High-grade dysplasia or invasive cancer on histological analysis of the surgical specimen
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Jean-Baptiste CHEVAUX
🇫🇷Nancy, France