ITMCTR1900002492Not yet recruiting未知
Study on Yanglingquan-gallbladder-central correlation based on multi-modal synchronous acquisition and fusion analysis
Chengdu University of Traditional Chinese Medicine0 sitesStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Not yet recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional study
Eligibility Criteria
- Ages
- 20 to 55 (—)
- Sex
- All
Inclusion Criteria
- •Subjects with cholelithiasis (gallstones)
- •(1)The diameters of gallstones in gallbladder are less than 1 cm;
- •(2) Right-handed;
- •(3) Aged between 20 to 50 years old;
- •(4) In the past half month, no cholecystolic and anti-infective drugs were taken, and no other clinical researchers will be involved;
- •(5) The informed consent is signed.
- •Note: Patients who meet the above five criteria can be included in this study.
- •Subjects after cholecystectomy
- •(1) Cholecystectomy (extrahepatic bile duct preservation) for cholelithiasis (intragallstone) has been performed for at least one year;
- •(2) No post-cholecystectomy syndrome such as epigastric or right epigastric pain, postprandial abdominal distention, dyspepsia, biliary tract infection or biliary obstruction occurred in the past three months;
- •(3) Right-handed persons aged between 20 to 55 years old;
- •(4) After physical examination, all physiological indicators are within the normal range. There are no functional or organic diseases and no head injuries in the past;
- •(5) No family history of mental and nervous system heredity;
- •(6)Subjects signed the paper version of informed consent and volunteered to participate in the experiment;
- •At the same time, all subjects who meet the above inclusion criteria will be considered for inclusion.
- •Healthy subjects:
- •(1) Right-handed persons aged 20 years or less than 55 years;
- •(2) After physical examination, all physiological indicators were in normal range. There are no functional or organic diseases and no head injury in the past;
- •(3) No family genetic history of mental and nervous system;
- •(4) Subjects signed the paper version of informed consent and volunteered to participate in the experiment.
- •At the same time, all healthy subjects who meet the above inclusion criteria will be considered for inclusion.
Exclusion Criteria
- •Subjects with cholelithiasis (gallstones)
- •(1) Cholelithiasis occurs in the bile duct or in the gallbladder with a diameter of more than 1 cm;
- •(2) Acute attack of gallbladder colic, acute cholecystitis, acute suppurative, gangrenous, obstructive cholecystitis and gallbladder perforation with diffuse peritonitis;
- •(3) Severe history of gastric diseases, such as peptic ulcer, upper gastrointestinal bleeding and gastric tumors;
- •(4) Patients with previous severe intestinal diseases, such as ulcerative colitis, Crohn's disease and irritable bowel syndrome;
- •(5) Patients with severe endocrine and metabolic diseases and space-occupying diseases that significantly affect the results of the study;
- •(6) Primary diseases and psychiatric diseases such as cardiovascular and cerebrovascular diseases, liver and kidney;
- •(7)Pregnant and lactating women;
- •(8)Those with contraindication of fMRI acquisition;
- •(9)Patients with severe depression and anxiety symptoms;
- •(10)With obvious headache, migraine, head trauma history.
- •Note: Patients who meet any of the above criteria will be excluded.
- •Subjects after cholecystectomy
- •(1) Pregnant or lactating women;
- •(2) Patients with obvious headache, migraine and head trauma history;
- •(3) contraindication of fMRI acquisition;
- •(4) Those who are participating in other clinical trials.
- •Note: Patients who meet any of the above criteria will be excluded.
- •Healthy subjects
- •(1) Pregnant or lactating women;
- •(2) Patients with history of head trauma;
- •(3) contraindication of fMRI;
- •(4) Those who are participating in other clinical trials.
- •Healthy subjects who meet any of the above criteria will be excluded.
Investigators
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