The Ability of Brain Waves Activity to Detect Patient Susceptibility to Post-Operative Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- brain wave activity
研究概览
简要总结
This observational study evaluates whether resting-state EEG alpha activity can help identify endodontic patients at higher risk of post-operative pain following single-visit root canal treatment. EEG will be recorded before treatment and pain intensity will be self-reported using a Visual Analogue Scale (VAS) during the early post-treatment period.
详细描述
This observational clinical study is designed to examine the association between resting-state electroencephalography (EEG) alpha activity and the intensity of post-operative pain following single-visit root canal treatment. Participants will be recruited from an endodontic clinic after ethics committee approval. Resting-state EEG will be recorded using a wearable EEG system prior to treatment. Post-operative pain intensity will be assessed using a patient-reported Visual Analogue Scale (VAS) during the early post-treatment period.
Participants will be classified based on baseline alpha activity (e.g., lower versus higher alpha power range). Analyses will evaluate whether baseline EEG alpha measures are associated with subsequent pain ratings and whether differences in alpha activity relate to higher post-operative pain susceptibility. The goal is to determine whether EEG alpha activity may serve as a practical biomarker for post-endodontic pain susceptibility.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient's age ranges from 20-
- •Vital lower first molar with signs and symptoms of acute irreversible pulpitis and indicated for single visit root canal treatment.
- •Patients that had not received any medicinal therapy after endodontic treatment.
- •Patients who are mentally and physically capable to record pain intensity estimated every 6 hours after endodontic treatment using VAS.
排除标准
- •Patient systemic disease or neurogenic disease that contraindicates the use of the EEG or have sensitivity to the electrode material.
- •Cases that root canal treatment could not be finished in a single visit such as teeth with apical periodontitis, pulpal necrosis, chronic apical abscess.
- •Patients who took analgesics within 24 hours after endodontic treatment.
研究组 & 干预措施
patients with high alpha frequency ranging from 11 to 13.
干预措施: Detection of th alpha brain waves activity (Diagnostic Test)
patients with low alpha frequency preoperatively ranging from 8 to 10.
干预措施: Detection of th alpha brain waves activity (Diagnostic Test)
结局指标
主要结局
brain wave activity
时间窗: 24 hours
The primary outcome is the correlation between pre-operative brain wave activity and post-operative pain intensity
次要结局
未报告次要终点