Merck IISP Stewardship Grant for Antibiotic Best Practices

Completed

• Conditions: Antibiotic Resistant Infection

• Registration Number: NCT01573195
• Lead Sponsor: University of Wisconsin, Madison

Brief Summary

The purpose of this study is to pilot the use of best practices alerts to enhance an antimicrobial stewardship program using the electronic medical record, EPIC.

Detailed Description

The purpose of this study is to pilot the use of best practices to enhance an antimicrobial stewardship program using the electronic medical record, EPIC. Screening information technology tools via SETNET/Safety SUrveyor(Premier) and the electronic anti-infective order form would allow for sufficient medical record review to create best practices alerts for the purpose of appropriate de-escalation of anti-invectives.

Study Timeline

• Study Start: 2011-03
• Study First Submitted: 2011-05-04
• Primary Completion: 2012-04
• Study Completion: 2012-04
• Study First Submitted QC: 2012-04-04
• Study First Posted: 2012-04-06
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-16
• Last Update Posted: 2014-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1285

Inclusion Criteria

• Physicians with prescribing privileges at the UWHC

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of best practice alerts(BPA) that were completely accepted, partially accepted, or rejected within 72 hours of issuing the BPA	One Year	after issuing the BPA for deescalation, the responding healthcare provider will respond in one of the manners above

Secondary Outcome Measures

Name	Time	Method
The number and type of antiinfectives that were administered before and after(11days) the best practice alert is issued.	One year	The antiinfective use before and after the BPA will be analyzed in detail. The number of antibiotics, percentage decrease(or less likely increase) in antiinfectives in the 3 days before BPA , and 11 days after the BPA will be analyzed. A cost analysis will be performed. Patient outcomes will not be assessed.

Trial Locations

Locations (1)

University of Wisconsin Hospitals and Clinics; 🇺🇸 Madison, Wisconsin, United States