Rehydration of children with severe malnutrition and gastroenteritis
Phase 2
Not yet recruiting
- Conditions
- Diarrhoea Severe Acute MalnutritionPaediatrics
- Registration Number
- PACTR202103852542919
- Lead Sponsor
- Imperial College London
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Children with SAM criteria (defined as any of: mid-upper arm circumference (MUAC) <11.5cm, WHZ <-3SD or kwashiorkor)
Diarrhoea (>3 loose stool/day)
Signs of severe dehydration
Exclusion Criteria
Diarrhoea lasting more than 14-days
Known congenital or rheumatic heart disease
Refusal of consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie rehydration efficacy in severe acute malnutrition with gastroenteritis?
How does oral rehydration solution compare to intravenous therapy for children with SAM and diarrhea in clinical trials?
Are there specific biomarkers that predict successful rehydration outcomes in SAM patients with gastroenteritis?
What are the potential adverse events associated with rehydration therapies in children with severe acute malnutrition?
What combination therapies are being explored alongside rehydration for managing SAM and gastroenteritis in pediatric populations?