Short Time Low PEEP Challenge and Mini Fluid Challenge
- Conditions
- Intraoperative CareFluid Responsiveness
- Interventions
- Other: Fluid Loading
- Registration Number
- NCT05419570
- Lead Sponsor
- Istanbul Saglik Bilimleri University
- Brief Summary
Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy. Therefore evaluating fluid responsiveness prior to fluid loading is highly recommended. To the best of our knowledge there is no study comparing the abilities short time low PEEP challenge and mini fluid challenge in predicting fluid responsiveness.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 35
- Patients undergoing pancreaticoduodenectomy
- Body mass index (BMI) > 35 kg / m2
- any ventricular dysfunction
- Crs < 35 ml / cmH2O
- valvular heart disease
- ASA score > 3
- cardiac arrhythmia
- history of lung disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients Undergoing Pancreaticoduodenectomy Fluid Loading -
- Primary Outcome Measures
Name Time Method Difference between the abilities of two methods to predict fluid responsiveness defined as an increase in stroke volume index >15% after fluid loading one day Difference between the area under reciever operating characterisitcs curve of two methods
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Başakşehir Çam adn Sakura City Hospital
🇹🇷Istanbul, Turkey
Başakşehir Çam and Sakura City Hospital
🇹🇷Istanbul, Turkey