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Short Time Low PEEP Challenge and Mini Fluid Challenge

Completed
Conditions
Intraoperative Care
Fluid Responsiveness
Interventions
Other: Fluid Loading
Registration Number
NCT05419570
Lead Sponsor
Istanbul Saglik Bilimleri University
Brief Summary

Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy. Therefore evaluating fluid responsiveness prior to fluid loading is highly recommended. To the best of our knowledge there is no study comparing the abilities short time low PEEP challenge and mini fluid challenge in predicting fluid responsiveness.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
35
Inclusion Criteria
  • Patients undergoing pancreaticoduodenectomy
Exclusion Criteria
  • Body mass index (BMI) > 35 kg / m2
  • any ventricular dysfunction
  • Crs < 35 ml / cmH2O
  • valvular heart disease
  • ASA score > 3
  • cardiac arrhythmia
  • history of lung disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients Undergoing PancreaticoduodenectomyFluid Loading-
Primary Outcome Measures
NameTimeMethod
Difference between the abilities of two methods to predict fluid responsiveness defined as an increase in stroke volume index >15% after fluid loadingone day

Difference between the area under reciever operating characterisitcs curve of two methods

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Başakşehir Çam adn Sakura City Hospital

🇹🇷

Istanbul, Turkey

Başakşehir Çam and Sakura City Hospital

🇹🇷

Istanbul, Turkey

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