Efficacy of enteral nutrition with commercial formula and Taurine Supplementation on Clinical outcome and nutritional status of Critically Ill burned patients in burned intensive care unit
Not Applicable
- Conditions
- T30-2, T30burn.Burn of second degree, body region unspecified, Burn of third degree, body region unspecified
- Registration Number
- IRCT201307082017N13
- Lead Sponsor
- Research Center of Infectious and Tropical Diseases, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Burned patients between the age18 and 85 years with total body surface area of burn more 20%; enteral feeding requirement of at least 48 h and expected length of >48h stay in the ICU; patients without hepatic failure; renal failure; inborn errors of amino-acid metabolism; metabolic acidosis(pH less7.35); absolute contraindication to enteral nutrition; non pregnant woman.
Exclusion criteria:
patients who died before the end of intervention; patients unable to tolerate enteral feeding.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical outcome measurement. Timepoint: day 1,3,6,9. Method of measurement: Sequential Organ Failure Assessment(SOFA) score.
- Secondary Outcome Measures
Name Time Method Effect on Immune System. Timepoint: Baseline and end of intervention. Method of measurement: TNF-alpha(ELISA test), Interleukin 10(IL-10)(ELISA test), High sensitivity C reactive protein( hs-CRP)(ELISA test).;Effect on Nutritional Status. Timepoint: Baseline and end of intervention. Method of measurement: Prealbumin (Immunoturbidometric assay).