An investigation of blood clots and other complications related to longer peripheral intravenous catheters in childre

Not Applicable

Completed

• Conditions: Catheter-related venous thrombosis; Catheter-related bloodstream infection; Local infection; Catheter dislodgement; Tissue infiltration; Mechanical complications; Anaesthesiology - Other anaesthesiology; Blood - Clotting disorders; Infection - Other infectious diseases

• Registration Number: ACTRN12619000472178
• Lead Sponsor: Department of Paediatric Perioperative Medicine and Intensive Care, Karolinska University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-21
• Study Completion: 2021-07-02
• Last Update Posted: 27 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All children receiving midline catheters at Astrid Lindgren Children´s hospital.

Exclusion Criteria

Previous venous thrombosis in the cannulated vein

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of midline-related venous thrombosis assessed by ultrasonography[Duration of midline catheter. <br>Ultrasonography will be performed:<br>1. If clinical signs of venous thrombosis appear during the dwell-time of the midline catheter.<br>2. At the time of midline catheter removal to screen for asymptomatic venous thrombosis. ]

Secondary Outcome Measures

Name	Time	Method
Midline-related bloodstream infection. Defined as a laboratory-confirmed bloodstream infection in a patient who had a midline within the 48 hour period before the development of the bloodstream infection, and that is not related to an infection at another site.[Assessed 48 hours after midline removal.];Removal of midline catheter due to:<br>1. Mechanical complication to midline catheter (occlusion, dislodgement, extravasation) <br>2..Thrombophlebitis. <br>This will be assessed by the treating physician in charge of the patient. [Daily assessments until the catheter is removed. ];The need for additional venous access to complete intended therapy. Defined as a need to insert an additional venous access to complete the intended therapy due to premature dysfunction of the midline catheter. <br>The need for additional venous access will be decided by the treating physician in charge of the patient. [This will be assessed at the time of catheter removal. ]