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Clinical Trials/NCT02819700
NCT02819700
Completed
N/A

Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI)

Centre Hospitalier Universitaire, Amiens2 sites in 1 country49 target enrollmentJanuary 29, 2013

Overview

Phase
N/A
Intervention
Not specified
Conditions
Frontotemporal Dementia
Sponsor
Centre Hospitalier Universitaire, Amiens
Enrollment
49
Locations
2
Primary Endpoint
ISDC (Behavioural Dysexecutive Syndrome Inventory)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Behavioural disorders are very common right from the initial stage of dementia and contribute to loss of autonomy. Behavioural dysexecutive disorders have a particular status due to their prevalence and their diagnostic importance, as they often constitute the initial symptoms of Frontotemporal Dementia (FTD), Semantic Dementia (SD) and Huntington's disease (HD) and they are classically more frequent in vascular dementia (VaD) than in Alzheimer's disease (AD). The presence of these disorders at the stage of Mild Cognitive Impairment (MCI) has only been partially evaluated and would increase the risk of progression to dementia. These classical data are based on non-standardized assessments and non-validated diagnostic criteria. The Groupe de Reflexion pour l'Evaluation des Fonctions EXécutives (GREFEX) has developed a standardized assessment tool for behavioural dysexecutive disorders, the Behavioural Dysexecutive Syndrome Inventory (BDSI) and has validated diagnostic criteria for this syndrome.

Registry
clinicaltrials.gov
Start Date
January 29, 2013
End Date
January 28, 2018
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Support to the consultation memory for a neurological disease ( frontotemporal dementia , vascular dementia , Alzheimer's disease , mild cognitive disorder, Huntington's disease ( with genetic diagnosis confirmed : number of CAG triplets \> 36 symptomatic : UHDRS score ≥5 ) with MMS \> 15
  • Age 40 to 85 years
  • Informing reliable
  • Agreeing to participate in the study.

Exclusion Criteria

  • Presence of other disease disturbing behavior ( current depressive syndrome , schizophrenia, psychosis , past psychiatric disorders requiring a stay \> 2 days in a specialized environment ) or cognition (mental retardation , illiteracy , respiratory failure, kidney , liver , heart ) or preventing the realization of the tests ( perceptual or motor deficit ) intrecérébrale pacing therapy or stem cell transplant , patient protected ( under supervision or guardianship ) , pregnant and / or breastfeeding and lack of consent

Outcomes

Primary Outcomes

ISDC (Behavioural Dysexecutive Syndrome Inventory)

Time Frame: Day 0

Behavioural Dysexecutive Syndrome Inventory

Study Sites (2)

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