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Clinical Trials/NCT06073028
NCT06073028
Completed
Not Applicable

Model-based Cueing-as-needed for Walking in Parkinson's Disease

Henri Mondor University Hospital1 site in 1 country15 target enrollmentFebruary 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
Henri Mondor University Hospital
Enrollment
15
Locations
1
Primary Endpoint
Walking speed
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Correcting of the lack of regularity in steps is a key component of gait rehabilitation in Parkinson's disease. The proposal is to introduce adaptive spatial auditory cueing (ASAC) based on verbal instruction "lengthen the step" automatically delivered when the stride length decreased below a predetermined threshold. The present study compared the effect of usual rhythmic auditory cueing versus ASAC used during a walking training in Parkinson's disease.

Detailed Description

Correcting of the lack of regularity in steps is a key component of gait rehabilitation in Parkinson's disease. The proposal is to introduce adaptive spatial auditory cueing (ASAC) based on verbal instruction "lengthen the step" automatically delivered when the stride length decreased below a predetermined threshold. The present study compared the effect of usual rhythmic auditory cueing versus ASAC used during a walking training in Parkinson's disease. Fifteen patients with Parkinson's disease performed both interventions in randomized order, one week apart: a 20-minute walking training with rhythmic auditory cueing, in form of a metronome adjusted on 110% of the patient's own cadence, or ASAC delivered when the stride length is less than 110% of the patient's own stride length. Assessment criteria were walking distance covered during the intervention, speed, step length, cadence, coefficients of variation of step length and step duration, and indexes of spatial and temporal asymmetry during a walking test before and just after the intervention.

Registry
clinicaltrials.gov
Start Date
February 1, 2021
End Date
February 1, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Henri Mondor University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Emilie Hutin

Director

Henri Mondor University Hospital

Eligibility Criteria

Inclusion Criteria

  • the diagnosis of idiopathic PD based on the United Kingdom-Parkinson's Disease Society Brain Bank criteria;
  • stage 2 or 3 on the Hoehn and Yahr scale;
  • comfortable walking speed over 10 meters ≤ 1 m/s;
  • ability to walk over 20 minutes without aids or antiparkinsonian medications;
  • a stable antiparkinsonian medication regime;
  • cognitive abilities to understand the verbal instructions for a walking test according to the investigator's judgment;
  • written consent for the participation.

Exclusion Criteria

  • intercurrent disease other than PD, affecting gait;
  • any intercurrent medical condition preventing them from participating in two consecutive gait training one week apart;
  • medical diagnosis of hearing loss;
  • non-affiliation to the social security regime.

Outcomes

Primary Outcomes

Walking speed

Time Frame: Before and just after the intervention

Speed in free walking condition over 10 meters barefoot, without any assistance

Study Sites (1)

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