Comparison of Manual Ventilation and Automatic Mechanical Ventilation During Cardiopulmonary Resuscitation, Pilot & Feasibility Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- ROSC: return of spontaneous circulation
研究概览
简要总结
Comparison of Manual Ventilation and Automatic Mechanical Ventilation during CPR, Pilot & Feasibility Study (CAVE-I trial)
详细描述
This is a preliminary randomized clinical trials comparing the effectiveness of the automatic mechanical ventilation method compared to manual ventilation methods commonly performed during advanced cardiac life support (ACLS) in emergency room for out-of-hospital cardiac arrest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Out-of-hospital cardiac arrest (OHCA)
- •Transferred by only EMS without prehospital return of spontaneous circulation (ROSC)
- •ACLS for at least 20 minutes in the emergency room
- •Arterial blood gas analysis at least once during ACLS
排除标准
- •In-hospital cardiac arrest (IHCA)
- •Not transferred by Emergency Medical Service
- •ROSC gained before arriving at the ER
- •OHCA caused by trauma
- •ACLS is not performed for more than 20 minutes because the death is obvious
- •Not able to intubate the trachea
研究组 & 干预措施
Automatic Mechanical Ventilation
Automatic Mechanical Ventilation during ACLS
干预措施: Automatic Mechanical Ventilation (Device)
Manual Ventilation
Standard care with manual ventilation, Ambu-bagging, during ACLS
干预措施: Manual Ventilation (Device)
结局指标
主要结局
ROSC: return of spontaneous circulation
时间窗: Within 20 minutes of ACLS
Rate of any ROSC after ACLS
次要结局
- Arterial blood gas analysis (ABGA) parameters(The first test was conducted within 5 minutes of ACLS, and the second test 10 minutes after the first test.)
- Ventilation parameters(During the entire ACLS time after randomization and endotracheal intubation)
研究者
Jong Hwan Shin
Associate Professor
Seoul National University Hospital