A Comparison Between Child-Pugh and Albumin-Bilirubin Scores
Completed
- Conditions
- Rupture, SpontaneousHepatocellular CarcinomaRupture LiverHepatic Impairment
- Registration Number
- NCT03534843
- Lead Sponsor
- Huazhong University of Science and Technology
- Brief Summary
To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma
- Detailed Description
To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma. And to determine which is better in predicting long-term survival and short-term survival.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 230
Inclusion Criteria
- Be diagnosed as hepatocellular carcinoma pathologically; had a tumor rupture confirmed by Intraperitoneal exploration or clinical signs and symptoms in combination with imaging examination.
Exclusion Criteria
- Be diagnosed as not hepatocellular carcinoma pathologically；had repeated transcatheter arterial chemoembolization(TACE) or a long history (more than 1 year) of cancer treatment; loss of follow up or without complete data.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival of all patients 5 years Overall survival of all patients among different Child-Pugh and albumin-bilirubin scores
- Secondary Outcome Measures
Name Time Method Short-term mortality of non-surgical subgroup Ninety days Ninety-day mortality of the non-surgical subgroup among different Child-Pugh and albumin-bilirubin scores
Short-term mortality of all patients Ninety days Ninety-day mortality of all patients among different Child-Pugh and albumin-bilirubin scores
Short-term mortality of surgical subgroup Ninety days Ninety-day mortality of the surgical subgroup among different Child-Pugh and albumin-bilirubin scores