The Dutch Multicentre Study Into Opportunistically Screening Geriatric Patients for Atrial Fibrillation Using a PPG Smartphone App; the Dutch-GERAF Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atrial Fibrillation
- Sponsor
- Dijklander Ziekenhuis
- Enrollment
- 1075
- Locations
- 6
- Primary Endpoint
- Newly identified cases of atrial fibrillation
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Geriatric patients are at high risk of cardiovascular complications, and for the development of atrial fibrillation. Often atrial fibrillation exists in these patients without specific symptoms, and could therefore remain unknown. Furthermore, concerns exist about the bleeding profile of anticoagulation in the very elderly or frail patients.
This study applies opportunistic screening for atrial fibrillation as advised in the latest ESC Guideline on the diagnosis and management of atrial fibrillation. Furthermore, multiple bleeding risk scores will be applies, to better assess the bleeding risk in very elderly or frail patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All newly referred patients of 65 years and older that visit geriatric outpatient services are eligible (including Fall clinic, Memory clinic, Pre-operative geriatric assessment clinic, or any other geriatric outpatient clinics that are led by a geriatrician).
Exclusion Criteria
- •The patient has a pacemaker or implantable cardioverter defibrillator.
- •The patient is known with a severe dementia, MoCA ≤ 15 points.
- •The patient has a severe tremor, from whatever cause, and thus is unable to use the PPG based smartphone AF detection algorithm.
Outcomes
Primary Outcomes
Newly identified cases of atrial fibrillation
Time Frame: The first 6 months after recruitment for the study
PPG or ECG detected new cases of atrial fibrillation
Secondary Outcomes
- Major bleeding(From recruitment until 3 years after the recruitment of the last participant)
- Stroke(From recruitment until 3 years after the recruitment of the last participant)
- Death(From recruitment until 3 years after the recruitment of the last participant)
- Cognitive disorder(From recruitment until 3 years after the recruitment of the last participant)
- New Atrial Fibrillation, developed after the screening period(From recruitment until 3 years after the recruitment of the last participant)