The Cohort Study of Uveitis Patients

Recruiting

• Conditions: Uveitis

• Registration Number: NCT05727540
• Lead Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Brief Summary

This study intends to explore the epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment of uveitis. This is a cohort study. The outcome of the study is the activity of inflammation and visual prognosis. The purpose of this study is to determine the optimal diagnosis and treatment scheme for uveitis patients based on real-world data.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-01-11
• Study First Submitted QC: 2023-02-03
• Study First Posted: 2023-02-14
• Study Start: 2023-02-20
• Status Verified: 2024-06
• Last Update Submitted: 2024-08-22
• Last Update Posted: 2024-08-23
• Primary Completion: 2026-02-20
• Study Completion: 2026-03-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

• The diagnosis is uveitis; The agreement of enrolling this study;

Exclusion Criteria

• Uveitis during the first month after any intraocular surgery; <18 years; pregnant and lactating women; other conditions are unsuitable for participation in this study by the investigator such as mental abnormalities.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The socre of anterior chamber inflammation based on the Standardization of Uveitis Nomenclature (SUN) scoring system	12 months post-treatment	activity of anterior chamber inflammation based on the Standardization of Uveitis Nomenclature (SUN) scoring system
The range of inflammatory chorioretinal and/or inflammatory retinal vascular lesions	12 months post-treatment	inflammatory chorioretinal and/or inflammatory retinal vascular lesions were evaluated by fundus fluorescein angiography and indocyanine green angiography

Secondary Outcome Measures

Name	Time	Method
The number of intraocular pressure	6 months post-treatment	The number of Intraocular pressure was examed by non-contact tonometer
The number of Intraocular pressure	36 months post-treatment	The number of Intraocular pressure was examed by non-contact tonometer
Central retinal thickness	36 months post-treatment	Central retinal thickness was evaluated by Optical Coherence Tomography
The range of inflammatory chorioretinal and/or inflammatory retinal vascular lesions	36 months post-treatment	inflammatory chorioretinal and/or inflammatory retinal vascular lesions were evaluated by fundus fluorescein angiography and indocyanine green angiography
Best corrected visual acuity	36 months post-treatment	Best corrected visual acuity
The socre of anterior chamber inflammation based on the Standardization of Uveitis Nomenclature (SUN) scoring system	36 months post-treatment	activity of anterior chamber inflammation based on the Standardization of Uveitis Nomenclature (SUN) scoring system

Trial Locations

Locations (1)

Zhongshan Ophthalmic Center; 🇨🇳 Guangzhou, Guangdong, China