A randomised prospective case control study on platelet rich plasma in male androgenetic alopecia and female pattern hair loss, and to compare pre and post treatment trichoscopic feature in male androgenetic alopecia female pattern hairloss
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Efficacy of platelet rich plasma in male and female andriogenetic alopecia in 100 patients
研究概览
简要总结
Male and Female androgenetic alopecia [MAGA and FAGA] is characterised by decreased hair scalp density and follicle miniaturisation of hair follicle. Topical minoxidil in female AGA and topical mionoxidil and oral finasteride are the only FDA approved therapy for female and male AGA.
Platelet rich plasma is a new and promising option to treat MAGA and FAGA, randomised controlled trials in indian patients are lacking. We will recruit 100 patient with grade 2-5 MAGA and FAGA for the study. Safety and efficacy of PRP in FAGA and MASGA will be studied based on global photographic assessment and trichoscopy in piolarised mode will be done in each case during 4 week follow up. Changes in hair density and number will be noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Treatment naive Grade 2-5 Male Androgenetic alopecia (Norwood hamilton scale) Grade 2-5 Female Androgenetic alopecia (Sinclair Scale).
排除标准
- •All pregnant females Those on any other hormonal therapy Grade 6 and 7 of hamilton norwood AGA patients.
结局指标
主要结局
Efficacy of platelet rich plasma in male and female andriogenetic alopecia in 100 patients
时间窗: Baseline, 4 weeks, 8weeks, 12 weeks, 16 weeks, 20 weeks, 24 weeks
次要结局
- Adverse effect(6 months)
研究者
Abhijeet Kumar Jha
Patna medical College