A COMPARATIVE CLINICAL STUDY OF KAMDUDHA RASA AND KUSHMANDA RASAYANA IN THE MANAGEMENT OF Gastro Esophageal Reflux Disese

Phase 2

Conditions: Health Condition 1: K219- Gastro-esophageal reflux disease without esophagitis

Registration Number: CTRI/2021/09/036819

Lead Sponsor: Al India Institute of Ayurveda

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

•Patient between the age group of 21 â?? 60 years

•Patients diagnosed as Amlapitta /GERD according to Ayurvedic classical features like Avipaka (Indigestion),Utklesha (Nausea),Hrit- Daha (Heartburn),Kantha-Daha(Throatburn),Tikta Udgara (Bitter eructations) ,Amla Udgara (Sour eructations), Chhardi (Vomiting),Aruchi(Anorexia) Shiro-Ruja(Headache). will be randomly selected irrespective of sex, religion and occupation.

•Chronicity < 6months

•The patients who are diagnosed with GERD according to GERDQ QUESTIONAIRE.

Exclusion Criteria

•Already diagnosed patient of chronic diseases (cardiovascular diseases, cancer, chronic respiratory diseases, diabetes, chronic orthopedic conditions) with early or late complication.

•Patient with the known organic cause of dyspepsia i.e gastric/duodenal ulcer. Patient on long term use of analgesic (atleast for 3 months).

•Patient with past history of Gastrointestinal (GI) surgery. Patient not suitable and contraindicated for therapy as assessed by the physician.

•Pregnant and lactating mothers.

•Patient with alarm features as Family history of upper GI malignancy in a first-degree relative, Unintended weight loss more than 5% of normal body weight over last 6â??12 months, Occult (elicited by past history) or overt GI bleeding (recent history of past 15 days to one month) or iron deficiency anemia, Dysphagia, Odynophagia, Persistent vomiting â??considered when there was more than 3 episodes of vomiting in 24 h in past 15 days to one month.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
â?¢Assessment of drug by biochemical and physiological parameters.Timepoint: â?¢3MONTHS

Secondary Outcome Measures

Name	Time	Method
â?¢Symptomatic and overall assessment will be discussed in subjective parameters. <br/ ><br>â?¢Improvement in quality of life. <br/ ><br>Timepoint: 3MONTHS