The Effect of Different Macronutrients on Appetite and Satiety in Older and Younger Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Ad-libitum meal consumption
研究概览
简要总结
This study aims to compare the effect of meals high in protein, fat and carbohydrate but equal in energy and volume on energy intake, perceived appetite and gastric emptying in younger (<40 years) and older (> 65 years) people living in the United Kingdom (UK).
详细描述
To assess if increasing protein intake in older adults will have a compensatory decrease in energy intake due to protein's satiating effects.
To compare the effect of meals high in protein, fat and carbohydrate but equal in energy and volume on energy intake and perceived appetite in younger (<40 years) and older adults (>65 years).
To compare the effect of meals high in protein, fat and carbohydrate but equal in energy and volume on gastric emptying in younger (<40 years) and older adults (>65 years).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •either aged >65 years or <40 years
排除标准
- •having a disease and/or using a medication that can impact on appetite in the past three months;
- •having an allergy to any of the test foods;
- •disliking or cannot eat any of the test foods;
- •being pregnant or breastfeeding;
- •being obese (BMI > 30 kg/m2);
- •being on a weight loss diet;
- •smoking more than 10 cigarettes a day.
结局指标
主要结局
Ad-libitum meal consumption
时间窗: 3 days in total
Consumption of the ad-libitum meal is measured (g). Participants are instructed to eat until they feel comfortable full and are given 20 min to consume the meal.
次要结局
- Ratings of appetite(3 days in total)
- Gastric Emptying(3 days in total)
- Ratings of palatability(3 days in total)
研究者
Miriam Clegg
Lecturer
University of Reading