A study for evaluating the effects of oral intake of lactic acid bacteria on immune function after exercise. A randomized, double-blind, placebo- controlled trial.
- Conditions
- one (Healthy adults)
- Registration Number
- JPRN-UMIN000020372
- Lead Sponsor
- Juntendo University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 70
Not provided
1)Individuals who can't stop drinking for 2 days before the days of screening and checkup. 2)Individuals who can't stop eating foods containing lactic acid bacteria and/or oligosaccharide, fermented foods during this study. 3)Individuals who can't stop eating functional foods which may affect immune functions. 4)Individuals who have a history of irritable bowel syndrome and Crohn's disease. 5) Individuals who have a medical history of serious disease (e.g., diabetes, liver disease, kidney disease, and/or heart disease), thyroid gland disease, adrenal gland disease, and/or metabolic disorder. 6)Individuals who have chronic diseases and use medicines continuously. 7)Individuals who have under treatment or a history of drug addiction and/or alcoholism. 8)Individuals who are judged as unsuitable for this study based on the results of blood test. 9)Individuals with excessive alcohol-drinking behaviors. 10)Individuals who have a medical history of diseases affecting digestion and absorption. 11)Individuals who are pregnant, breastfeeding, or planning to be pregnant in the near future. 12)Individuals who are participating or willing to participate in other clinical trials. 13)Individuals whose family works for a company manufacturing or selling healthy foods or functional foods. 14)Individuals with steroid treatment. 15)Individuals who are seropositive against HBV antigen, HCV antibody, HIV antibody, or HTLV-1 antibody. 16)Individuals who are judged unsuitable for this study by the investigator for other reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Activities of dendritic cells and the immune-reaction of peripheral blood mononuclear cells to the stimulation of inactivated viruses (interferon-alpha production, and anti-viral genes expression), conditioning questionnaire.
- Secondary Outcome Measures
Name Time Method Immune activity, stress hormone amount, and cytokine amount of blood, salivary immune activity and stress hormone amount, conditioning questionnaire.