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Melatonin and Adiponectin in Hypertensive Kidney Transplant

Completed
Conditions
Hypertension
Kidney Transplant
Registration Number
NCT00498576
Lead Sponsor
Sheba Medical Center
Brief Summary

Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.

The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus "normal" hypertensive patients. Secondly, to ask if there is any correlation between melatonin secretion and adiponectin levels.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • hypertension
  • kidney transplantation ( group 1)
  • good renal function
Exclusion Criteria
  • diabetes mellitus
  • cancer
  • renal failure

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Sheba Medical Center

🇮🇱

Ramat-gan, Israel

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