Registrated Cohort Study on Thrombectomy for Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Modified Rankin Scale
研究概览
简要总结
The cerebral collateral circulation refers to the subsidiary network of vascular channels that stabilize cerebral blood flow when principal conduits fail. Collateral status differs among patients with acute ischemic stroke. Relatively sparse attention has been devoted to the role of baseline collateral circulation in patients with acute ischemic stroke who are candidates for revascularization. This study aim to investigate the correlation between baseline collateral circulation and the likelihood of opening of an arterial occlusion, the extent of reperfusion, tissue injury and clinical impairment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years.
- •Mechanical thrombectomy initiated within 24 hours after onset
- •CT perfusion can be performed before the initiation of thrombectomy and 24h after thrombectomy
排除标准
- •Contraindication to imaging with contrast agents
- •Delay between imaging and beginning of thrombectomy > 90 minutes
结局指标
主要结局
Modified Rankin Scale
时间窗: 3 month
Good functional outcome will be defined by a Modified Rankin Scale of 0-2, 3 months after stroke onset
次要结局
未报告次要终点
研究者
Ning Wang, MD., PhD.
Director of Neurology department
First Affiliated Hospital of Fujian Medical University