A Cohort Study on Thrombectomy for Stroke

Recruiting

• Conditions: Ischemic Stroke

• Registration Number: NCT04637074
• Lead Sponsor: Ning Wang, MD., PhD.

Brief Summary

The cerebral collateral circulation refers to the subsidiary network of vascular channels that stabilize cerebral blood flow when principal conduits fail. Collateral status differs among patients with acute ischemic stroke. Relatively sparse attention has been devoted to the role of baseline collateral circulation in patients with acute ischemic stroke who are candidates for revascularization. This study aim to investigate the correlation between baseline collateral circulation and the likelihood of opening of an arterial occlusion, the extent of reperfusion, tissue injury and clinical impairment.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-15
• Study First Submitted: 2020-11-15
• Study First Submitted QC: 2020-11-15
• Study First Posted: 2020-11-19
• Status Verified: 2021-11
• Last Update Submitted: 2021-12-27
• Last Update Posted: 2021-12-29
• Primary Completion: 2025-12-30
• Study Completion: 2025-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Age ≥ 18 years.
• Mechanical thrombectomy initiated within 24 hours after onset
• CT perfusion can be performed before the initiation of thrombectomy and 24h after thrombectomy

Exclusion Criteria

• Contraindication to imaging with contrast agents
• Delay between imaging and beginning of thrombectomy > 90 minutes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Modified Rankin Scale	3 month	Good functional outcome will be defined by a Modified Rankin Scale of 0-2, 3 months after stroke onset

Trial Locations

Locations (1)

Department of Neurology, First Affiliated Hospital of Fujian Medical University; 🇨🇳 Fuzhou, China